- kboguslawski@health.ucsd.edu
- (858) 534-9760
-
3147 Biomedical Sciences Way, Mail code 0760
Israni BRFII Room 4220
Mail Code: 0760
La Jolla , California 92093
Kristina Boguslawski
PEDS ID Clinical Fellow
- Interests
- Background and Education
- Honors and Publications
Interests
Research Interests
- Host-Pathogen Interactions
- Novel Antimicrobial Therapies
- Proteomics
At the Bench
Kristina is a pediatric infectious disease fellow interested in basic and translational research of invasive bacterial infections. Originally from Western Massachusetts, she first got started in research at UMASS Amherst as an undergraduate, studying quorum sensing in the model gram positive bacterium Bacillus subtilis. She then completed MD PhD training at NYU School of Medicine studying Staphylococcus aureus leukotoxins under the mentorship of Victor Torres before moving to San Diego for residency and fellowship in Peds ID through the Pediatric Scientist Training Program. Kristina will join the Nizet lab and Gonzalez lab in summer of 2025 and plans to take a proteomics approach to uncover host-microbe interactions and further the development of novel therapeutics to treat antimicrobial resistant pathogens.
Outside of Lab
Kristina enjoys lifting heavy weights, walking everywhere, yoga, and a smattering of other active and outdoor activities. She also likes live music, board game nights with friends, and visiting the local libraries.
Background and Education
Education
| University | Degree | Year | Field |
| UCSD Rady Children's Hospital, San Diego CA | Clinical Fellowship | 2024-Present | Pediatric Infectious Diseases |
| UCSD Rady Children's Hospital, San Diego CA | Residency | 2022-2024 | Pediatrics |
| NYU School of Medicine | MD | 2022 | Medicine |
| NYU School of Medicine | Ph.D. | 2019 | Microbiology |
| UMass Amherst, Amherst MA | M.S. | 2013 | Microbiology |
| UMass Amherst, Amherst MA | B.S. | 2012 | Microbiology |
Honors and Publications
Honors
| Year | Honor |
| 2025-2027 | Pediatric Scientist Development Program (PSDP) Award |
| 2016-2018 | Vilcek MSTP Scholar Award |
| 2012 | Phi Beta Kappa Honor Society |
| 2011 | HHMI Summer Research Fellow |
Publications
Lubkin A, Bernard-Raichon L, DuMont AL, Valero Jimenez AM, Putzel GG, Gago J, Zwack EE, Olusanya O, Boguslawski K, Dallari S, Dyzenhaus S, Herrmann C, Ilmain JK, Isom GL, Pawline M, Perault AI, Perelman S, Sause WE, Shahi I, St John A, … Torres VJ. SARS-CoV-2 infection predisposes patients to coinfection with Staphylococcus aureus. mBio. 2024. PMID: 39037272.
Langouët-Astrié C, Oshima K, McMurtry SA, Yang Y, Kwiecinski JM, LaRivière WB, Kavanaugh JS, Zakharevich I, Hansen KC, Shi D, Zhang F, Boguslawski KM, Perelman SS, Su G, Torres VJ, Liu J, Horswill AR, Schmidt EP. The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia. Cell Rep. 2022. PMID: 36450248.
Perelman SS*, James DBA*, Boguslawski KM*, Nelson CW, Ilmain JK, Zwack EE, Prescott RA, Mohamed A, Tam K, Chan R, Narechania A, Pawline MB, Vozhilla N, Moustafa AM, Kim SY, Dittman M, Ekiert DC, Bhabha G, Shopsin B, Planet PJ, Torres VJ. Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat. Microbiol. 2021. PMID: 33875847. *authors contributed equally to this work.
Shewell LK, Day CJ, Jen FE, Haselhorst T, Atack JM, Reijveveld JF, Everest-Dass A, James DBA, Boguslawski KM, Brouwer S, Gillen CM, Luo Z, Kobe B, Nizet V, Itzstein M, Walker MJ, Paton AW, Paton JC, Torres VJ, Jennings MP. All major cholesterol-dependent cytolysins use glycans as cellular receptors. Sci Adv. 2020. PMID: 32494740.
Boguslawski KM, McKeown AN, Day CJ, Tam K, Vozhilla N, Kim SY, Jennings MP, Koralov SB, Elde NC, Torres VJ. Exploiting species specificity to understand the tropism of a human specific toxin. Sci Adv. 2020. PMID: 32195339.
Chan R, Buckley PT, O'Malley A, Sause WE, Alonzo F 3rd, Lubkin A, Boguslawski KM, Payne A, Fernandez J, Strohl WR, Whitaker B, Lynch AS, Torres VJ. Identification of novel biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus. Sci Transl Med. 2019. PMID: 30651319.
Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE Jr. Monoclonal antibodies against the Staphylococcus aureus bicomponent Leukotoxin AB isolated following invasive human infection reveal diverse binding and modes of action. J Infect Dis. 2017. PMID: 28186295
Spaan AN, Reyes-Robles T, Badiou C, Cochet S, Boguslawski KM, Yoong P, Day CJ, de Haas CJ, van Kessel KP, Vandenesch F, Jennings MP, Le Van Kim C, Colin Y, van Strijp JA, Henry T, Torres VJ. Staphylococcus aureus targets the Duffy Antigen Receptor for Chemokines (DARC) to lyse erythrocytes. Cell Host Microbe. 2015. PMID: 26320997.
Boguslawski KM, Hill PA, Griffith KL. Novel mechanisms of controlling the activities of the transcription factors Spo0A and ComA by the plasmid-encoded quorum sensing regulators Rap60-Phr60 in Bacillus subtilis. Mol Microbiol. 2015. PMID: 25598361