- snordenfelt@health.ucsd.edu
- (858) 534-9760
-
3147 Biomedical Sciences Way, Mail code 0760
Israni BRFII Room 4220
Mail Code: 0760
La Jolla , California 92093
Susanne Nordenfelt
Visiting Scholar
- Interests
- Background and Education
- Honors and Publications
Interests
Research Interests
- NETs
- Inflammation
- Rheumatic Diseases
At the Bench
Susanne is from Sweden and her career in science started with a Masters degree in Biomedicine at Umeå University. From there she moved back to southern Sweden to start her PhD with Hakon Leffler in the field of glycobiology, charting the glycan preference of the two carbohydrate binding domains of Galectin-8. New experiences awaited at Statens Serum Institut in Copenhagen where she was trying to find novel viruses in respiratory diseases as well as diagnosing influenza in patients during the swine flu pandemic. Working with viruses was the perfect background for her job as a researcher in David Reichs lab at Harvard Medical School, Boston, sequencing minute amounts of ancient DNA in their newly started clean room. Back in Sweden Susanne went to medical school and is now pursuing a residency in Rheumatology at Lund University Hospital. The visit to Victor Nizet lab is giving her a possibility to study the central process of NETs close-up, laying a foundation for continued research within inflammatory diseases.
Outside of Lab
Susanne enjoys spending time with her husband and four kids. They play board games, watch movies, host dinners or go for walks. She loves nature with all its animals, birds and plants, and also baking.
Background and Education
Academic Appointments
| Year | Position |
| 2025-2026 | Visiting Scholar, Victor Nizet Lab, Department of Pediatrics, UCSD |
| 2012-2014 | Researcher, David Reich Lab, Harvard Medical School, Boston |
| 2008-2012 | Research Scientist, Statens Serum Institut, Copenhagen, Denmark |
Education
| University | Degree | Year | Field |
| Skåne's University Hospital | Residency | 2022-Present | Rheumatology |
| Skåne's University Hospital | Internship | 2020-2022 | Medicine |
| Lund University, Sweden | MD | 2015-2020 | Medicine |
| Lund University, Sweden | Ph.D. | 2000-2007 | Glycobiology |
| Umeå University, Sweden | M.Sc. | 1996-2000 | Biomedicine |
Honors and Publications
Publications
Harney, É; May, H; Shalem, D; Rohland, N; Mallick, S; Lazaridis, I; Sarig, R; Stewardson, K; Nordenfelt, S; Patterson, N et al. ”Ancient DNA from Chalcolithic Israel reveals the role of population mixture in cultural transformation” Nature Communications. 2018.
Lipson, M; Szécsényi-Nagy, A; Mallick, S; Pósa, A; Stégmár, B; Keerl, V; Rohland, N; Stewardson, K; Ferry, M; Michel, M et al. “Parallel palaeogenomic transects reveal complex genetic history of early European farmers” Nature. 2017.
Mallick, S; Li, H; Lipson, M; Mathieson, I; Gymrek, M; Racimo, F; Zhao, M; Chennagiri, N; Nordenfelt, S; Tandon, A et al. ”The Simons genome diversity project: 300 genomes from 142 diverse populations” Nature. 2016.
Llamas, B; Fehren-Schmitz, L; Valverde, G; Soubrier, J; Mallick, S; Rohland, N; Nordenfelt, S; Valdiosera, C; Richards, S; Rohrlach, A et al. ”Ancient mitochondrial DNA provides high-resolution time scale of the peopling of the Americas.” Science Advances. 2016.
Sudmant, P; Mallick, S; Nelson, B; Hormozdiari, F; Krumm, N; Huddleston, J; Coe, B; Baker, C; Nordenfelt, S; Bamshad, M et al. ”Global diversity, population stratification, and selection of human copy-number variation.” Science. 2015.
Fehren-Schmitz, L; Llamas, B; Lindauer, S; Tomasto-Cagigao, E; Kuzminsky, S; Rohland, N; Santos, F; Kaulicke, P; Valverde, G; Richards, S et al. ”A re-appraisal of the early Andean human remains from Lauricocha in Peru.” PLoS ONE. 2015.
Haak, W; Lazaridis, I; Patterson, N; Rohland, N; Mallick, S; Llamas, B; Brandt, G; Nordenfelt, S; Harney, E; Stewardson, K et al. ”Massive migration from the steppe was a source for Indo-European languages in Europe.” Nature. 2015.
Rohland, N; Harney, E; Mallick, S; Nordenfelt, S; Reich, D. “Partial uracil-DNA-glycosylase treatment for screening of ancient DNA.” Philos Trans R Soc Lond B Biol Sci. 2015.
Lazaridis, I; Patterson, N; Mittnik, A; Renaud, G; Mallick, S; Sudmant, P; Schraiber, J; Castellano, S; Kirsanow, K; Economou, C et al. ”Ancient human genomes suggest three ancestral populations for present-day Europeans”. Nature. 2014.
Carlsson S. ”Galectin-8 specificity to cells: from broad outside to fine inside.” PhD thesis. 2007 Lund University.
Carlsson, S; Carlsson, MC; Leffler, H. ”Intracellular sorting of galectin-8 based on carbohydrate fine specificity.” Glycobiology. 2007.
Carlsson S, Oberg CT, Carlsson MC, Sundin A, Nilsson UJ et al. “Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface.” Glycobiology. 2007.
Aplander, K; Tejler, J; Toftered, J; Carlsson, S; Kahl-Knutsson, B; Sundin, A; Leffler, H; Nilsson, U; ”Synthesis of a 3′-naphthamido-LacNAc fluorescein conjugate with high selectivity and affinity for galectin-3.” Carbohydrate research. 2006.
Patnaik, S; Potvin, B; Carlsson, S; Sturm, D; Leffler, H; Stanley, P. “Complex N-glycans are the major ligands for galectin-1,-3, and-8 on Chinese hamster ovary cells.” Glycobiology. 2005.
Cumpstey, I; Carlsson, S; Leffler, H; Nilsson, U. ”Synthesis of a phenyl thio-β-D-galactopyranoside library from 1, 5-difluoro-2, 4-dinitrobenzene: discovery of efficient and selective monosaccharide inhibitors of galectin-7.” Organic & biomolecular chemistry. 2005.
Leffler H, Carlsson S, Hedlund M, Qian Y, Poirier F. ”Introduction to galectins.” Glycoconj J. 2004.
Öberg, C; Carlsson, S; Fillion, E; Leffler, H; Nilsson, U. ”Efficient and expedient two-step pyranose-retaining fluorescein conjugation of complex reducing oligosaccharides: galectin oligosaccharide specificity studies in a fluorescence polarization assay.” Bioconjugate chemistry. 2003
Lipson, M; Szécsényi-Nagy, A; Mallick, S; Pósa, A; Stégmár, B; Keerl, V; Rohland, N; Stewardson, K; Ferry, M; Michel, M et al. “Parallel palaeogenomic transects reveal complex genetic history of early European farmers” Nature. 2017.
Mallick, S; Li, H; Lipson, M; Mathieson, I; Gymrek, M; Racimo, F; Zhao, M; Chennagiri, N; Nordenfelt, S; Tandon, A et al. ”The Simons genome diversity project: 300 genomes from 142 diverse populations” Nature. 2016.
Llamas, B; Fehren-Schmitz, L; Valverde, G; Soubrier, J; Mallick, S; Rohland, N; Nordenfelt, S; Valdiosera, C; Richards, S; Rohrlach, A et al. ”Ancient mitochondrial DNA provides high-resolution time scale of the peopling of the Americas.” Science Advances. 2016.
Sudmant, P; Mallick, S; Nelson, B; Hormozdiari, F; Krumm, N; Huddleston, J; Coe, B; Baker, C; Nordenfelt, S; Bamshad, M et al. ”Global diversity, population stratification, and selection of human copy-number variation.” Science. 2015.
Fehren-Schmitz, L; Llamas, B; Lindauer, S; Tomasto-Cagigao, E; Kuzminsky, S; Rohland, N; Santos, F; Kaulicke, P; Valverde, G; Richards, S et al. ”A re-appraisal of the early Andean human remains from Lauricocha in Peru.” PLoS ONE. 2015.
Haak, W; Lazaridis, I; Patterson, N; Rohland, N; Mallick, S; Llamas, B; Brandt, G; Nordenfelt, S; Harney, E; Stewardson, K et al. ”Massive migration from the steppe was a source for Indo-European languages in Europe.” Nature. 2015.
Rohland, N; Harney, E; Mallick, S; Nordenfelt, S; Reich, D. “Partial uracil-DNA-glycosylase treatment for screening of ancient DNA.” Philos Trans R Soc Lond B Biol Sci. 2015.
Lazaridis, I; Patterson, N; Mittnik, A; Renaud, G; Mallick, S; Sudmant, P; Schraiber, J; Castellano, S; Kirsanow, K; Economou, C et al. ”Ancient human genomes suggest three ancestral populations for present-day Europeans”. Nature. 2014.
Carlsson S. ”Galectin-8 specificity to cells: from broad outside to fine inside.” PhD thesis. 2007 Lund University.
Carlsson, S; Carlsson, MC; Leffler, H. ”Intracellular sorting of galectin-8 based on carbohydrate fine specificity.” Glycobiology. 2007.
Carlsson S, Oberg CT, Carlsson MC, Sundin A, Nilsson UJ et al. “Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface.” Glycobiology. 2007.
Aplander, K; Tejler, J; Toftered, J; Carlsson, S; Kahl-Knutsson, B; Sundin, A; Leffler, H; Nilsson, U; ”Synthesis of a 3′-naphthamido-LacNAc fluorescein conjugate with high selectivity and affinity for galectin-3.” Carbohydrate research. 2006.
Patnaik, S; Potvin, B; Carlsson, S; Sturm, D; Leffler, H; Stanley, P. “Complex N-glycans are the major ligands for galectin-1,-3, and-8 on Chinese hamster ovary cells.” Glycobiology. 2005.
Cumpstey, I; Carlsson, S; Leffler, H; Nilsson, U. ”Synthesis of a phenyl thio-β-D-galactopyranoside library from 1, 5-difluoro-2, 4-dinitrobenzene: discovery of efficient and selective monosaccharide inhibitors of galectin-7.” Organic & biomolecular chemistry. 2005.
Leffler H, Carlsson S, Hedlund M, Qian Y, Poirier F. ”Introduction to galectins.” Glycoconj J. 2004.
Öberg, C; Carlsson, S; Fillion, E; Leffler, H; Nilsson, U. ”Efficient and expedient two-step pyranose-retaining fluorescein conjugation of complex reducing oligosaccharides: galectin oligosaccharide specificity studies in a fluorescence polarization assay.” Bioconjugate chemistry. 2003