Publications

Identification of a colonial chordate histocompatibility gene. 

The genome sequence of the colonial chordate, Botryllus schlosseri. 
Discriminating cellular heterogeneity using microwell-based RNA cytometry. 

Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. 

MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. 

Single-cell dissection of transcriptional heterogeneity in human colon tumors. 

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. 

Gene Expression Commons: an open platform for absolute gene expression profiling.  

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development .

MiDReG: a method of mining developmentally regulated genes using Boolean implications .

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. 

Three differentiation states risk-stratify bladder cancer into distinct subtypes. 

Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. 

Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis. 

Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. 

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors .

Extracting binary signals from microarray time-course data .

Boolean implication networks derived from large scale, whole genome microarray datasets .

Drosophila lin-52 acts in opposition to repressive components of the Myb-MuvB/dREAM complex .

The power of boolean implication networks.Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells.