Research
Gabriel Haddad, MD
Dr. Haddad studies the role of ion channels in nerve cells in a low O2 environment. He is also interested in the genetics of susceptibility or tolerance to low or high O2 and the role of gene expression in excitable tissues. He also studies obstructive sleep apnea and the role of hypoxia and hypercapnia on growth and development.
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Kathryn Akong, MD, PhD
Dr. Akong completed fellowship training in June, 2011, and joined the faculty as Assistant Professor. She is the site PI at Rady Children's Hospital for the Cystic Fibrosis Therapeutics Development Network . She collaborates closely with Dr. Victor Nizet (Pharmacology and Drug Discovery) to investigate novel modalities to treat patients with cystic fibrosis.
Priti Azad, PhD
Dr. Azad studies mechanisms by which intermittent (e.g., obstructive sleep apnea and sickle cell anemia) and constant hypoxia (e.g., asthma) lead to cell injury and morbidity or adaptation and survival using Drosophila as well as cell culture model systems.
Daniel Lesser, MD
Dr. Lesser is involved in clinical research investigating the role of sleep disordered breathing in metabolic disease.
Paul Quinton, PhD
Dr. Quinton investigates the effects of the genetic defects in fluid and electrolyte transport in cystic fibrosis on pathophysiology in the airways, intestine, and sweat glands in cystic fibrosis and related diseases.
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Julie Ryu, MD
Dr. Ryu studies innovative methodologies including remote monitoring of asthma management and bronchoscopy as a potential tool to diagnose asthma in children.
A.K.M. Shamsuddin, PhD
Dr. Shamsuddin studies β-adrenergic sweat stimulation, sweat diagnostic testing and electrolyte transport across normal and cystic fibrosis sweat gland and native small and large airway (pigs and humans) epithelia.
Xin Sun, PhD
Dr. Sun studies several aspects of molecular biology of the lung from investigating how the lung is a sensory organ through pulmonary neuroendocrine cells, mechanisms of lung maturation to genetics of modeling lung disease.
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Jin Xue, MD, PhD
Dr. Xue studies the genetic and molecular basis of sodium hydrogen exchanger isoform 1 (NHE1)-mediated cardiac injury.
Hang Yao, PhD
Dr. Yao studies the cellular and molecular mechanisms of penumbral cell death in focal cerebral ischemia.
Ning Yang, MD, PhD
Dr. Yang investigates the role of HCO3- in normal mucus formation/release and how to correct the abnormal mucus in cystic fibrosis in the intestine and other associated organs.
Huiwen Zhao, PhD
Dr. Zhao studies mechanisms of hypoxia adaptation using induced pluripotent stem cells-derived neurons obtained from patients with chronic mountain sickness
Dan Zhou, PhD
Dr. Zhou studies the genetic and molecular mechanisms underlying hypoxia and hyperoxia adaptation and tolerance.