Vilar-Gomez E, Yates KP, Kleiner DE, Behling C, Cummings OW, Wilson LA, Liang T, Jarasvaraparn C, Loomba R, Schwimmer JB, Sanyal AJ, Hoofnagle J, Chalasani N. Genetic and non-genetic drivers of histological progression and regression in MASLD. J Hepatol. 2025 Sep 23:S0168-8278(25)02493-6. doi: 10.1016/j.jhep.2025.09.013. Epub ahead of print. PMID: 40998180; PMCID: PMC12495455.
Cohen CC, Dabelea D, Davy BM, Glueck DH, Newton KP, Perng W, Welsh JA, Schwimmer JB, Vos MB. Responsiveness of the Serum Carbon Isotope Ratio to Dietary Added Sugar Reduction in a Randomized Controlled Trial among Youth with Steatotic Liver Disease. J Nutr. 2025 Aug 12:S0022-3166(25)00484-5. doi: 10.1016/j.tjnut.2025.08.006. Epub ahead of print. PMID: 40812479; PMCID: PMC12459073.
Thai NQN, Goyal NP, Newton KP, Schwimmer JB. Reply: Blood pressure adjustment and competing risks analysis should be reconsidered in the mortality exploration among children with MASLD. Hepatology. 2025 Aug 4. doi: 10.1097/HEP.0000000000001486. Epub ahead of print. PMID: 40758394.
Schwimmer JB, Biddinger SB, Ibrahim SH. MASLD in children: integrating epidemiological trends with mechanistic and translational advances. J Clin Invest. 2025 Jul 1;135(13):e186422. doi: 10.1172/JCI186422. PMID: 40590222; PMCID: PMC12208537.
Hartmann P, Mouzaki M, Hassan S, Kehar M, Mysore KR, Mauney E, Nonga D, Karjoo S, Sood S, Tou A, Brichta C, Herdes RE, Pai N, Garner DK, Rinella ME, Noureddin M, Younossi Z, Allen AM, Sanyal A, Kohut T, Kohli R, Ramirez CM, Xanthakos S, Vos MB, Schwimmer JB, Ibrahim SH, Panganiban J. Call to action-Pediatric MASLD requires immediate attention to curb health crisis. Hepatology. 2025 Jun 23:10.1097/HEP.0000000000001440. doi: 10.1097/HEP.0000000000001440. Epub ahead of print. PMID: 40550108; PMCID: PMC12236211.
Hakim A, Lin KH, Schwantes-An TH, Abreu M, Tan J, Guo X, Yates KP, Lotta L, Verweij N, Loomba R, Kleiner DE, Schwimmer JB, Rotter JI, Chalasani NP. A comprehensive evaluation of candidate genetic polymorphisms in a large histologically characterized MASLD cohort using a novel framework. Hepatol Commun. 2025 May 29;9(6):e0728. doi: 10.1097/HC9.0000000000000728. PMID: 40434633; PMCID: PMC12122170.
Schwimmer JB, Stein MB, Coccaro EF, Meruelo AD. Exploring the metabolic signature of intermittent explosive disorder: Preliminary evidence and potential mechanisms for altered bilirubin metabolism. Compr Psychoneuroendocrinol. 2025 Apr 22;22:100294. doi: 10.1016/j.cpnec.2025.100294. PMID: 40342636; PMCID: PMC12060501.
Xanthakos SA, Ibrahim SH, Adams K, Kohli R, Sathya P, Sundaram S, Vos MB, Dhawan A, Caprio S, Behling CA, Schwimmer JB. AASLD Practice Statement on the evaluation and management of metabolic dysfunction-associated steatotic liver disease in children. Hepatology. 2025 Apr 29. doi: 10.1097/HEP.0000000000001368. Epub ahead of print. PMID: 40300071.
Schwimmer JB, Thai NQN, Noon SL, Ugalde-Nicalo P, Anderson SR, Chun LF, David RS, Goyal NP, Newton KP, Hansen EG, Lin B, Shapiro WL, Wang A, Yu EL, Behling CA. Long-term mortality and extrahepatic outcomes in 1096 children with MASLD: A retrospective cohort study. Hepatology. 2025 Apr 22:10.1097/HEP.0000000000001357. doi: 10.1097/HEP.0000000000001357. Epub ahead of print. PMID: 40262118; PMCID: PMC12353144.
Noon SL, Lam TBN, Schwimmer JB. Editorial: Prevalence of Suspected Metabolic Dysfunction-Associated Liver Disease in Adolescents in the United States Using Updated Diagnostic Criteria-Authors' Reply. Aliment Pharmacol Ther. 2025 May;61(9):1557-1558. doi: 10.1111/apt.70092. Epub 2025 Mar 16. PMID: 40091192.
Noon SL, Chun LF, Lam TBN, Thai NQN, Dunn W, Schwimmer JB. Prevalence and Predictors of Suspected Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents in the United States. Aliment Pharmacol Ther. 2025 May;61(9):1479-1488. doi: 10.1111/apt.70022. Epub 2025 Feb 12. PMID: 39943715; PMCID: PMC11981549.
Zifan A, Zhao K, Lee M, Peng Z, Roney LJ, Pai S, Weeks JT, Middleton MS, Kaffas AE, Schwimmer JB, Sirlin CB. Adaptive Evolutionary Optimization of Deep Learning Architectures for Focused Liver Ultrasound Image Segmentation. Diagnostics (Basel). 2025 Jan 7;15(2):117. doi: 10.3390/diagnostics15020117. PMID: 39857001; PMCID: PMC11763560.
Newton KP, Jayasekera D, Blackford AL, Behling C, Wilson LA, Fishbein MH, Molleston JP, Xanthakos SA, Vos MB, Schwimmer JB; NASH CRN. Longitudinal response to standard of care in pediatric metabolic dysfunction-associated steatotic liver disease: Rates of improvement and worsening, and factors associated with outcomes. Hepatology. 2025 Jan 3:10.1097/HEP.0000000000001216. doi: 10.1097/HEP.0000000000001216. Epub ahead of print. PMID: 39773889; PMCID: PMC12222545.
Smith MR, Yu EL, Malki GJ, Newton KP, Goyal NP, Heskett KM, Schwimmer JB. Systematic review of exercise for the treatment of pediatric metabolic dysfunction-associated steatotic liver disease. PLoS One. 2024 Dec 10;19(12):e0314542. doi: 10.1371/journal.pone.0314542. PMID: 39656734; PMCID: PMC11630624
Jain AK, Busgang SA, Gennings C, Yates KP, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Carpenter D, Fishbein M, Neuschwander-Tetri BA, Tonasia J, Vos MB. Environmental toxicants modulate disease severity in pediatric metabolic dysfunction-associated steatohepatitis. J Pediatr Gastroenterol Nutr. 2024 Nov;79(5):943-953. doi: 10.1002/jpn3.12346. Epub 2024 Sep 16. PMID: 39282813; PMCID: PMC11955998.
Yu EL, You H, Rudolph B, Panganiban JA, Kohut TJ, Lin HC, Fifi AC, Budhathoki R, Butler MW, Anderson SR, Goyal NP, Newton KP, Schwimmer JB. Patient perspective on exercise practices, preferences, and barriers in pediatric nonalcoholic fatty liver disease: A multicenter survey. JPGN Rep. 2024 Apr 12;5(3):317-325. doi: 10.1002/jpr3.12072. PMID: 39149177; PMCID: PMC11322029.
Robinson MK, Lee E, Ugalde-Nicalo PA, Skonieczny JW, Chun LF, Newton KP, Schwimmer JB. Pentadecanoic Acid Supplementation in Young Adults with Overweight and Obesity: A Randomized Controlled Trial. J Nutr. 2024 Sep;154(9):2763-2771. doi: 10.1016/j.tjnut.2024.07.030. Epub 2024 Jul 26. PMID: 39069269.
Mouzaki M, Yates KP, Arce-Clachar AC, Behling C, Blondet NM, Fishbein MH, Flores F, Adams KH, Hertel P, Jain AK, Molleston JP, Schwimmer JB, Vos MB, Xanthakos SA; NASH Clinical Research Network. Renal impairment is prevalent in pediatric NAFLD/MASLD and associated with disease severity. J Pediatr Gastroenterol Nutr. 2024 Aug;79(2):238-249. doi: 10.1002/jpn3.12272. Epub 2024 Jun 3. PMID: 38828720; PMCID: PMC11956019.
Hildreth A, Schwimmer JB. Letter to the editor in response to: A case of pediatric alcohol-associated hepatitis evaluated for liver transplant listing. JPGN Rep. 2024 Feb 26;5(2):235. doi: 10.1002/jpr3.12026. PMID: 38756136; PMCID: PMC11093891.
Hildreth A, Schwimmer JB. Reply to letter to the editor in response to: Distinguishing autoimmune hepatitis from steatohepatitis in adolescents with obesity and positive screening alanine aminotransferase. JPGN Rep. 2024 Feb 12;5(2):240-241. doi: 10.1002/jpr3.12049. PMID: 38756115; PMCID: PMC11093905.
Huneault HE, Chen CY, Cohen CC, Liu X, Jarrell ZR, He Z, DeSantos KE, Welsh JA, Maner-Smith KM, Ortlund EA, Schwimmer JB, Vos MB. Lipidome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys with Metabolic Dysfunction-Associated Steatotic Liver Disease. Metabolites. 2024 Mar 28;14(4):191. doi: 10.3390/metabo14040191. PMID: 38668319; PMCID: PMC11052520.
Lee C, Schwimmer JB, Gunderson EP, Goyal NP, Darbinian JA, Greenspan LC, Lo JC. Alanine aminotransferase elevation varies by ethnicity among Asian and Pacific Islander children with overweight or obesity. Pediatr Obes. 2024 Jun;19(6):e13110. doi: 10.1111/ijpo.13110. Epub 2024 Mar 5. PMID: 38444225.
Shapiro WL, Kunani P, Sidell MA, Li X, Anderson SR, Slezak JM, Koebnick C, Schwimmer JB. Prevalence of Adolescents Meeting Criteria for Metabolic and Bariatric Surgery. Pediatrics. 2024 Mar 1;153(3):e2023063916. doi: 10.1542/peds.2023-063916. PMID: 38410833.
Hang Nghiem-Rao T, Johnson JS, Pan A, Atkinson SN, Behling C, Simpson PM, Holtz ML, Weinstock GM, Schwimmer JB, Salzman NH. A serum-induced gene signature in hepatocytes is associated with pediatric nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2024 Apr;78(4):886-897. doi: 10.1002/jpn3.12163. Epub 2024 Feb 23. PMID: 38390691; PMCID: PMC11967236.
Wang A, Blackford AL, Behling C, Wilson LA, Newton KP, Xanthakos SA, Fishbein MH, Vos MB, Mouzaki M, Molleston JP, Jain AK, Hertel P, Harlow Adams K, Schwimmer JB; NASH CRN. Development of Fibro-PeN, a clinical prediction model for moderate-to-severe fibrosis in children with nonalcoholic fatty liver disease. Hepatology. 2024 Jun 1;79(6):1381-1392. doi: 10.1097/HEP.0000000000000644. Epub 2023 Oct 23. PMID: 37870272; PMCID: PMC11035485.
Jain AK, Buchannan P, Yates KP, Belt P, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Hertel P, Nilson J, Neuschwander-Tetri BA, Tonascia J, Vos MB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Nutrition assessment and MASH severity in children using the Healthy Eating Index. Hepatol Commun. 2023 Dec 7;7(12):e0320. doi: 10.1097/HC9.0000000000000320. PMID: 38055641; PMCID: PMC10984667.
Wang A, Blackford AL, Behling C, Wilson LA, Newton KP, Xanthakos SA, Fishbein MH, Vos MB, Mouzaki M, Molleston JP, Jain AK, Hertel P, Harlow Adams K, Schwimmer JB; NASH CRN. Development of Fibro-PeN, a clinical prediction model for moderate-to-severe fibrosis in children with nonalcoholic fatty liver disease. Hepatology. 2024 Jun 1;79(6):1381-1392. doi: 10.1097/HEP.0000000000000644. Epub 2023 Oct 23. PMID: 37870272; PMCID: PMC11035485.
Lazarus JV, Mark HE, Allen AM, Arab JP, Carrieri P, Noureddin M, Alazawi W, Alkhouri N, Alqahtani SA, Arrese M, Bataller R, Berg T, Brennan PN, Burra P, Castro-Narro GE, Cortez-Pinto H, Cusi K, Dedes N, Duseja A, Francque SM, Hagström H, Huang TT, Wajcman DI, Kautz A, Kopka CJ, Krag A, Miller V, Newsome PN, Rinella ME, Romero D, Sarin SK, Silva M, Spearman CW, Tsochatzis EA, Valenti L, Villota-Rivas M, Zelber-Sagi S, Schattenberg JM, Wong VW, Younossi ZM; Healthy Livers, Healthy Lives Collaborators. A global research priority agenda to advance public health responses to fatty liver disease. J Hepatol. 2023 Sep;79(3):618-634. doi: 10.1016/j.jhep.2023.04.035. Epub 2023 Jun 20. PMID: 37353401.
Hildreth A, Shapiro WL, Lowenthal BM, Goyal A, Schwimmer JB. Distinguishing Autoimmune Hepatitis From Steatohepatitis in Adolescents With Obesity and Positive Screening Alanine Aminotransferase. JPGN Rep. 2023 Feb 28;4(2):e292. doi: 10.1097/PG9.0000000000000292. PMID: 37200725; PMCID: PMC10187841.
Mischel AK, Liao Z, Cao F, Dunn W, Lo JC, Newton KP, Goyal NP, Yu EL, Schwimmer JB. Prevalence of Elevated ALT in Adolescents in the US 2011-2018. J Pediatr Gastroenterol Nutr. 2023 Jul 1;77(1):103-109. doi: 10.1097/MPG.0000000000003795. Epub 2023 Apr 21. PMID: 37084344; PMCID: PMC10330162.
Goyal NP, Mencin A, Newton KP, Durelle J, Carrier C, Ugalde-Nicalo P, Noel B, Mouton J, Vargas D, Magrez D, Tadde B, Birman P, Best BM, Addy C, Schwimmer JB. An Open Label, Randomized, Multicenter Study of Elafibranor in Children With Nonalcoholic Steatohepatitis. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):160-165. doi: 10.1097/MPG.0000000000003796. Epub 2023 Apr 21. PMID: 37084342; PMCID: PMC10523882.
Malki GJ, Goyal NP, Ugalde-Nicalo P, Chun LF, Zhang J, Ding Z, Wei Y, Knott C, Batakis D, Henderson W, Sirlin CB, Middleton MS, Schwimmer JB. Association of Hepatic Steatosis with Adipose and Muscle Mass and Distribution in Children. Metab Syndr Relat Disord. 2023 May;21(4):222-230. doi: 10.1089/met.2023.0002. Epub 2023 Apr 20. PMID: 37083405; PMCID: PMC10181799.
Cohen CC, Huneault H, Accardi CJ, Jones DP, Liu K, Maner-Smith KM, Song M, Welsh JA, Ugalde-Nicalo PA, Schwimmer JB, Vos MB. Metabolome × Microbiome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys. Metabolites. 2023 Mar 8;13(3):401. doi: 10.3390/metabo13030401. PMID: 36984841; PMCID: PMC10053986.
Newton KP, Wilson LA, Crimmins NA, Fishbein MH, Molleston JP, Xanthakos SA, Behling C, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network. Incidence of Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2023 May;21(5):1261-1270. doi: 10.1016/j.cgh.2022.05.028. Epub 2022 Jun 13. PMID: 35709934; PMCID: PMC10151072.
Goyal NP, Rosenthal SB, Nasamran C, Behling CA, Angeles JE, Fishbein MH, Harlow KE, Jain AK, Molleston JP, Newton KP, Ugalde-Nicalo P, Xanthankos SA, Yates K, Schork NJ, Fisch KM, Schwimmer JB; NASH Clinical Research Network. Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children. Hepatology. 2023 Jan 1;77(1):197-212. doi: 10.1002/hep.32570. Epub 2022 Jun 20. PMID: 35560106; PMCID: PMC9653518.
Newton KP, Wilson LA, Crimmins NA, Fishbein MH, Molleston JP, Xanthakos SA, Behling C, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network. Incidence of Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2023 May;21(5):1261-1270. doi: 10.1016/j.cgh.2022.05.028. Epub 2022 Jun 13. PMID: 35709934; PMCID: PMC10151072.
Vujkovic M, Ramdas S, Lorenz KM, Guo X, Darlay R, Cordell HJ, He J, Gindin Y, Chung C, Myers RP, Schneider CV, Park J, Lee KM, Serper M, Carr RM, Kaplan DE, Haas ME, MacLean MT, Witschey WR, Zhu X, Tcheandjieu C, Kember RL, Kranzler HR, Verma A, Giri A, Klarin DM, Sun YV, Huang J, Huffman JE, Creasy KT, Hand NJ, Liu CT, Long MT, Yao J, Budoff M, Tan J, Li X, Lin HJ, Chen YI, Taylor KD, Chang RK, Krauss RM, Vilarinho S, Brancale J, Nielsen JB, Locke AE, Jones MB, Verweij N, Baras A, Reddy KR, Neuschwander-Tetri BA, Schwimmer JB, Sanyal AJ, Chalasani N, Ryan KA, Mitchell BD, Gill D, Wells AD, Manduchi E, Saiman Y, Mahmud N, Miller DR, Reaven PD, Phillips LS, Muralidhar S, DuVall SL, Lee JS, Assimes TL, Pyarajan S, Cho K, Edwards TL, Damrauer SM, Wilson PW, Gaziano JM, O'Donnell CJ, Khera AV, Grant SFA, Brown CD, Tsao PS, Saleheen D, Lotta LA, Bastarache L, Anstee QM, Daly AK, Meigs JB, Rotter JI, Lynch JA; Regeneron Genetics Center; Geisinger-Regeneron DiscovEHR Collaboration; EPoS Consortium; VA Million Veteran Program; Rader DJ, Voight BF, Chang KM. A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. Nat Genet. 2022 Jun;54(6):761-771. doi: 10.1038/s41588-022-01078-z. Epub 2022 Jun 2. PMID: 35654975; PMCID: PMC10024253.
Goyal NP, Rosenthal SB, Nasamran C, Behling CA, Angeles JE, Fishbein MH, Harlow KE, Jain AK, Molleston JP, Newton KP, Ugalde-Nicalo P, Xanthankos SA, Yates K, Schork NJ, Fisch KM, Schwimmer JB; NASH Clinical Research Network. Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children. Hepatology. 2023 Jan 1;77(1):197-212. doi: 10.1002/hep.32570. Epub 2022 Jun 20. PMID: 35560106; PMCID: PMC9653518.
Vos MB, Van Natta ML, Blondet NM, Dasarathy S, Fishbein M, Hertel P, Jain AK, Karpen SJ, Lavine JE, Mohammad S, Miriel LA, Molleston JP, Mouzaki M, Sanyal A, Sharkey EP, Schwimmer JB, Tonascia J, Wilson LA, Xanthakos SA; NASH Clinical Research Network. Randomized placebo-controlled trial of losartan for pediatric NAFLD. Hepatology. 2022 Aug;76(2):429-444. doi: 10.1002/hep.32403. Epub 2022 Feb 28. PMID: 35133671; PMCID: PMC9288975.
Wu SJ, Darbinian JA, Schwimmer JB, Yu EL, Ramalingam ND, Greenspan LC, Lo JC. The Prevalence of Elevated Alanine Aminotransferase Levels Meeting Clinical Action Thresholds in Children with Obesity in Primary Care Practice. J Pediatr. 2022 Jan;240:280-283. doi: 10.1016/j.jpeds.2021.09.033. Epub 2021 Sep 23. PMID: 34562443; PMCID: PMC8841387.
Cohen CC, Li KW, Alazraki AL, Beysen C, Carrier CA, Cleeton RL, Dandan M, Figueroa J, Knight-Scott J, Knott CJ, Newton KP, Nyangau EM, Sirlin CB, Ugalde-Nicalo PA, Welsh JA, Hellerstein MK, Schwimmer JB, Vos MB. Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease. J Clin Invest. 2021 Dec 15;131(24):e150996. doi: 10.1172/JCI150996. PMID: 34907907; PMCID: PMC8670836.
Wu SJ, Darbinian JA, Schwimmer JB, Yu EL, Ramalingam ND, Greenspan LC, Lo JC. The Prevalence of Elevated Alanine Aminotransferase Levels Meeting Clinical Action Thresholds in Children with Obesity in Primary Care Practice. J Pediatr. 2022 Jan;240:280-283. doi: 10.1016/j.jpeds.2021.09.033. Epub 2021 Sep 23. PMID: 34562443; PMCID: PMC8841387.
Shapiro WL, Noon SL, Schwimmer JB. Recent advances in the epidemiology of nonalcoholic fatty liver disease in children. Pediatr Obes. 2021 Nov;16(11):e12849. doi: 10.1111/ijpo.12849. Epub 2021 Sep 9. PMID: 34498413; PMCID: PMC8807003.
Salzman NH, Schwimmer JB. Pediatric nonalcoholic fatty liver disease and the microbiome: Mechanisms contributing to pathogenesis and progression. Curr Opin Endocr Metab Res. 2021 Aug;19:22-29. doi: 10.1016/j.coemr.2021.05.003. Epub 2021 May 17. PMID: 34222711; PMCID: PMC8248528.
Qu Y, Middleton MS, Loomba R, Glaser KJ, Chen J, Hooker JC, Wolfson T, Covarrubias Y, Valasek MA, Fowler KJ, Zhang YN, Sy E, Gamst AC, Wang K, Mamidipalli A, Schwimmer JB, Song B, Reeder SB, Yin M, Ehman RL, Sirlin CB. Magnetic resonance elastography biomarkers for detection of histologic alterations in nonalcoholic fatty liver disease in the absence of fibrosis. Eur Radiol. 2021 Nov;31(11):8408-8419. doi: 10.1007/s00330-021-07988-6. Epub 2021 Apr 26. PMID: 33899143; PMCID: PMC8530863.
Hong CW, Cui JY, Batakis D, Xu Y, Wolfson T, Gamst AC, Schlein AN, Negrete LM, Middleton MS, Hamilton G, Loomba R, Schwimmer JB, Fowler KJ, Sirlin CB. Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. Abdom Radiol (NY). 2021 Jul;46(7):3105-3116. doi: 10.1007/s00261-021-02965-5. Epub 2021 Feb 20. PMID: 33609166; PMCID: PMC8983333.
Chun LF, Yu EL, Sawh MC, Bross C, Nichols J, Polgreen L, Knott C, Schlein A, Sirlin CB, Middleton MS, Kado DM, Schwimmer JB. Hepatic Steatosis is Negatively Associated with Bone Mineral Density in Children. J Pediatr. 2021 Jun;233:105-111.e3. doi: 10.1016/j.jpeds.2021.01.064. Epub 2021 Feb 3. PMID: 33545191; PMCID: PMC8154638.
Sawh MC, Wallace M, Shapiro E, Goyal NP, Newton KP, Yu EL, Bross C, Durelle J, Knott C, Gangoiti JA, Barshop BA, Gengatharan JM, Meurs N, Schlein A, Middleton MS, Sirlin CB, Metallo CM, Schwimmer JB. Dairy Fat Intake, Plasma Pentadecanoic Acid, and Plasma Iso-heptadecanoic Acid Are Inversely Associated With Liver Fat in Children. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):e90-e96. doi: 10.1097/MPG.0000000000003040. PMID: 33399331; PMCID: PMC8842839.
Noon SL, D'Annibale DA, Schwimmer MH, Shiels J, Arin J, Durelle J, Newton KP, Goyal NP, Schwimmer JB. Incidence of Depression and Anxiety in a Cohort of Adolescents With Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):579-583. doi: 10.1097/MPG.0000000000003024. PMID: 33346572; PMCID: PMC8815421.
Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. Hepatology. 2021 Mar;73(3):937-951. doi: 10.1002/hep.31317. Epub 2020 Nov 30. PMID: 32416645; PMCID: PMC7669708.
Sahota AK, Shapiro WL, Newton KP, Kim ST, Chung J, Schwimmer JB. Incidence of Nonalcoholic Fatty Liver Disease in Children: 2009-2018. Pediatrics. 2020 Dec;146(6):e20200771. doi: 10.1542/peds.2020-0771. PMID: 33214329; PMCID: PMC7706110.
Xanthakos SA, Lavine JE, Yates KP, Schwimmer JB, Molleston JP, Rosenthal P, Murray KF, Vos MB, Jain AK, Scheimann AO, Miloh T, Fishbein M, Behling CA, Brunt EM, Sanyal AJ, Tonascia J; NASH Clinical Research Network. Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice. Gastroenterology. 2020 Nov;159(5):1731-1751.e10. doi: 10.1053/j.gastro.2020.07.034. Epub 2020 Jul 23. PMID: 32712103; PMCID: PMC7680281.
Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. Hepatology. 2021 Mar;73(3):937-951. doi: 10.1002/hep.31317. Epub 2020 Nov 30. PMID: 32416645; PMCID: PMC7669708.
Mamidipalli A, Fowler KJ, Hamilton G, Wolfson T, Covarrubias Y, Tran C, Fazeli S, Wiens CN, McMillan A, Artz NS, Funk LM, Campos GM, Greenberg JA, Gamst A, Middleton MS, Schwimmer JB, Reeder SB, Sirlin CB. Prospective comparison of longitudinal change in hepatic proton density fat fraction (PDFF) estimated by magnitude-based MRI (MRI-M) and complex-based MRI (MRI-C). Eur Radiol. 2020 Sep;30(9):5120-5129. doi: 10.1007/s00330-020-06858-x. Epub 2020 Apr 21. PMID: 32318847; PMCID: PMC7495399.
Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S, Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C; NASH Clinical Research Network. Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH. Hepatology. 2020 Oct;72(4):1219-1229. doi: 10.1002/hep.31121. Epub 2020 Oct 9. PMID: 31965579; PMCID: PMC8055244.
Cunha GM, Thai TT, Hamilton G, Covarrubias Y, Schlein A, Middleton MS, Wiens CN, McMillan A, Agni R, Funk LM, Campos GM, Horgan S, Jacobson G, Wolfson T, Gamst A, Schwimmer JB, Reeder SB, Sirlin CB. Accuracy of common proton density fat fraction thresholds for magnitude- and complex-based chemical shift-encoded MRI for assessing hepatic steatosis in patients with obesity. Abdom Radiol (NY). 2020 Mar;45(3):661-671. doi: 10.1007/s00261-019-02350-3. PMID: 31781899; PMCID: PMC8108484.
Goyal NP, Sawh MC, Ugalde-Nicalo P, Angeles JE, Proudfoot JA, Newton KP, Middleton MS, Sirlin CB, Schwimmer JB. Evaluation of Quantitative Imaging Biomarkers for Early-phase Clinical Trials of Steatohepatitis in Adolescents. J Pediatr Gastroenterol Nutr. 2020 Jan;70(1):99-105. doi: 10.1097/MPG.0000000000002535. PMID: 31633654; PMCID: PMC8053386.
Sawh MC, Newton KP, Goyal NP, Angeles JE, Harlow K, Bross C, Schlein AN, Hooker JC, Sy EZ, Glaser KJ, Yin M, Ehman RL, Sirlin CB, Schwimmer JB. Normal range for MR elastography measured liver stiffness in children without liver disease. J Magn Reson Imaging. 2020 Mar;51(3):919-927. doi: 10.1002/jmri.26905. Epub 2019 Aug 27. PMID: 31452280; PMCID: PMC7386297.
Vos MB, Dimick-Santos L, Mehta R, Omokaro SO, Taminiau J, Schabel E, Kleiner DE, Szitanyi P, Socha P, Schwimmer JB, Noviello S, Silberg DG, Torstenson R, Miller V, Lavine JE; Liver Forum Pediatric Working Group. Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease. Gastroenterology. 2019 Dec;157(6):1448-1456.e1. doi: 10.1053/j.gastro.2019.08.048. Epub 2019 Sep 12. PMID: 31520612; PMCID: PMC8996263.
Sawh MC, Newton KP, Goyal NP, Angeles JE, Harlow K, Bross C, Schlein AN, Hooker JC, Sy EZ, Glaser KJ, Yin M, Ehman RL, Sirlin CB, Schwimmer JB. Normal range for MR elastography measured liver stiffness in children without liver disease. J Magn Reson Imaging. 2020 Mar;51(3):919-927. doi: 10.1002/jmri.26905. Epub 2019 Aug 27. PMID: 31452280; PMCID: PMC7386297.
Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock GM, Salzman NH. Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2019 Oct;157(4):1109-1122. doi: 10.1053/j.gastro.2019.06.028. Epub 2019 Jun 27. PMID: 31255652; PMCID: PMC6756995.
Schwimmer JB, Ugalde-Nicalo P, Vos MB. Low Free Sugar Diet in Adolescents With Nonalcoholic Fatty Liver Disease-Reply. JAMA. 2019 Jun 25;321(24):2469. doi: 10.1001/jama.2019.5153. PMID: 31237636. Hong CW, Hamilton G, Hooker C, Park CC, Tran CA, Henderson WC, Hooker JC, Fazeli Dehkordy S, Schwimmer JB, Reeder SB, Sirlin CB. Measurement of spleen fat on MRI-proton density fat fraction arises from reconstruction of noise. Abdom Radiol (NY). 2019 Oct;44(10):3295-3303. doi: 10.1007/s00261-019-02079-z. PMID: 31172210; PMCID: PMC7275729.
Corey KE, Wilson LA, Altinbas A, Yates KP, Kleiner DE, Chung RT, Krauss RM, Chalasani N; NASH Clinical Research Network. Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial. Aliment Pharmacol Ther. 2019 May;49(9):1205-1213. doi: 10.1111/apt.15216. Epub 2019 Mar 10. PMID: 30854694; PMCID: PMC6461513.
Covarrubias Y, Fowler KJ, Mamidipalli A, Hamilton G, Wolfson T, Leinhard OD, Jacobsen G, Horgan S, Schwimmer JB, Reeder SB, Sirlin CB. Pilot study on longitudinal change in pancreatic proton density fat fraction during a weight-loss surgery program in adults with obesity. J Magn Reson Imaging. 2019 Oct;50(4):1092-1102. doi: 10.1002/jmri.26671. Epub 2019 Jan 30. PMID: 30701611; PMCID: PMC6667307.
Schwimmer JB, Ugalde-Nicalo P, Welsh JA, Angeles JE, Cordero M, Harlow KE, Alazraki A, Durelle J, Knight-Scott J, Newton KP, Cleeton R, Knott C, Konomi J, Middleton MS, Travers C, Sirlin CB, Hernandez A, Sekkarie A, McCracken C, Vos MB. Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys: A Randomized Clinical Trial. JAMA. 2019 Jan 22;321(3):256-265. doi: 10.1001/jama.2018.20579. Erratum in: JAMA. 2019 Aug 6;322(5):469. doi: 10.1001/jama.2019.10532. PMID: 30667502; PMCID: PMC6440226.
Shapiro WL, Yu EL, Arin JC, Murray KF, Ali S, Desai NK, Xanthakos SA, Lin HC, Alkhouri N, Abdou R, Abrams SH, Butler MW, Faasse SA, Gillis LA, Hadley TA, Jain AK, Kavan M, Kordy K, Lee P, Panganiban J, Pohl JF, Potter C, Rudolph B, Sundaram SS, Joshi S, Proudfoot JA, Goyal NP, Harlow KE, Newton KP, Schwimmer JB. Clinical Practice Approach to Nonalcoholic Fatty Liver Disease by Pediatric Gastroenterologists in the United States. J Pediatr Gastroenterol Nutr. 2019 Feb;68(2):182-189. doi: 10.1097/MPG.0000000000002194. PMID: 30640271; PMCID: PMC8053385.
Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis. J Clin Gastroenterol. 2019 Nov/Dec;53(10):750-758. doi: 10.1097/MCG.0000000000001142. PMID: 30586008; PMCID: PMC6588507.
Pooler BD, Wiens CN, McMillan A, Artz NS, Schlein A, Covarrubias Y, Hooker J, Schwimmer JB, Funk LM, Campos GM, Greenberg JA, Jacobsen G, Horgan S, Wolfson T, Gamst AC, Sirlin CB, Reeder SB. Monitoring Fatty Liver Disease with MRI Following Bariatric Surgery: A Prospective, Dual-Center Study. Radiology. 2019 Mar;290(3):682-690. doi: 10.1148/radiol.2018181134. Epub 2018 Dec 18. PMID: 30561273; PMCID: PMC6394737.
Yu EL, Golshan S, Harlow KE, Angeles JE, Durelle J, Goyal NP, Newton KP, Sawh MC, Hooker J, Sy EZ, Middleton MS, Sirlin CB, Schwimmer JB. Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity. J Pediatr. 2019 Apr;207:64-70. doi: 10.1016/j.jpeds.2018.11.021. Epub 2018 Dec 14. PMID: 30559024; PMCID: PMC6440815.
Newfield RS, Graves CL, Newbury RO, Schwimmer JB, Proudfoot JA, Say DS, Feldstein AE. Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects. Pediatr Diabetes. 2019 Feb;20(1):41-47. doi: 10.1111/pedi.12798. Epub 2018 Dec 9. PMID: 30467936.
Nobili V, Schwimmer JB, Vajro P. Breastfeeding and NAFLD from the maternal side of the mother-infant dyad. J Hepatol. 2019 Jan;70(1):13-14. doi: 10.1016/j.jhep.2018.10.030. Epub 2018 Nov 7. PMID: 30414736.
Pooler BD, Wiens CN, McMillan A, Artz NS, Schlein A, Covarrubias Y, Hooker J, Schwimmer JB, Funk LM, Campos GM, Greenberg JA, Jacobsen G, Horgan S, Wolfson T, Gamst AC, Sirlin CB, Reeder SB. Monitoring Fatty Liver Disease with MRI Following Bariatric Surgery: A Prospective, Dual-Center Study. Radiology. 2019 Mar;290(3):682-690. doi: 10.1148/radiol.2018181134. Epub 2018 Dec 18. PMID: 30561273; PMCID: PMC6394737.
Yu EL, Golshan S, Harlow KE, Angeles JE, Durelle J, Goyal NP, Newton KP, Sawh MC, Hooker J, Sy EZ, Middleton MS, Sirlin CB, Schwimmer JB. Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity. J Pediatr. 2019 Apr;207:64-70. doi: 10.1016/j.jpeds.2018.11.021. Epub 2018 Dec 14. PMID: 30559024; PMCID: PMC6440815.
Newfield RS, Graves CL, Newbury RO, Schwimmer JB, Proudfoot JA, Say DS, Feldstein AE. Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects. Pediatr Diabetes. 2019 Feb;20(1):41-47. doi: 10.1111/pedi.12798. Epub 2018 Dec 9. PMID: 30467936.
Nobili V, Schwimmer JB, Vajro P. Breastfeeding and NAFLD from the maternal side of the mother-infant dyad. J Hepatol. 2019 Jan;70(1):13-14. doi: 10.1016/j.jhep.2018.10.030. Epub 2018 Nov 7. PMID: 30414736.
Elbel EE, Lavine JE, Downes M, Van Natta M, Yu R, Schwimmer JB, Behling C, Brunt EM, Tonascia J, Evans R. Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2018 Sep 27;2(10):1213-1226. doi: 10.1002/hep4.1232. PMID: 30288476; PMCID: PMC6167075.
Schwimmer MH, Sawh MC, Heskett KM, Goyal NP, Newton KP, Schwimmer JB. A Bibliometric Analysis of Clinical and Translational Research in Pediatric Gastroenterology From 1970 to 2017. J Pediatr Gastroenterol Nutr. 2018 Nov;67(5):564-569. doi: 10.1097/MPG.0000000000002056. PMID: 29901549; PMCID: PMC6203653.
Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease. J Pediatr. 2018 Jul;198:76-83.e2. doi: 10.1016/j.jpeds.2018.02.038. Epub 2018 Apr 13. PMID: 29661561; PMCID: PMC6019181.
Rausch JC, Lavine JE, Chalasani N, Guo X, Kwon S, Schwimmer JB, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Rotter JI; NASH Clinical Research Network. Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2018 May;66(5):789-796. doi: 10.1097/MPG.0000000000001926. PMID: 29470286; PMCID: PMC5916321.
Luo RB, Suzuki T, Hooker JC, Covarrubias Y, Schlein A, Liu S, Schwimmer JB, Reeder SB, Funk LM, Greenberg JA, Campos GM, Sandler BJ, Horgan S, Sirlin CB, Jacobsen GR. How bariatric surgery affects liver volume and fat density in NAFLD patients. Surg Endosc. 2018 Apr;32(4):1675-1682. doi: 10.1007/s00464-017-5846-9. Epub 2017 Dec 7. PMID: 29218660; PMCID: PMC6690434.
Bydder M, Hamilton G, de Rochefort L, Desai A, Heba ER, Loomba R, Schwimmer JB, Szeverenyi NM, Sirlin CB. Sources of systematic error in proton density fat fraction (PDFF) quantification in the liver evaluated from magnitude images with different numbers of echoes. NMR Biomed. 2018 Jan;31(1):10.1002/nbm.3843. doi: 10.1002/nbm.3843. Epub 2017 Nov 12. PMID: 29130539; PMCID: PMC5761676.
Goyal NP, Schwimmer JB. The Genetics of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2018 Feb;22(1):59-71. doi: 10.1016/j.cld.2017.08.002. Epub 2017 Oct 5. PMID: 29128061; PMCID: PMC5693307.
Middleton MS, Van Natta ML, Heba ER, Alazraki A, Trout AT, Masand P, Brunt EM, Kleiner DE, Doo E, Tonascia J, Lavine JE, Shen W, Hamilton G, Schwimmer JB, Sirlin CB; NASH Clinical Research Network. Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease. Hepatology. 2018 Mar;67(3):858-872. doi: 10.1002/hep.29596. Epub 2018 Jan 26. PMID: 29028128; PMCID: PMC6211296.
Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB. Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2018 Feb;47(2):418-424. doi: 10.1002/jmri.25748. Epub 2017 May 25. PMID: 28543915; PMCID: PMC5702271.
Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network. In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. Clin Gastroenterol Hepatol. 2018 Mar;16(3):438-446.e1. doi: 10.1016/j.cgh.2017.02.030. Epub 2017 Mar 7. PMID: 28286193; PMCID: PMC5589478.
Luo RB, Suzuki T, Hooker JC, Covarrubias Y, Schlein A, Liu S, Schwimmer JB, Reeder SB, Funk LM, Greenberg JA, Campos GM, Sandler BJ, Horgan S, Sirlin CB, Jacobsen GR. How bariatric surgery affects liver volume and fat density in NAFLD patients. Surg Endosc. 2018 Apr;32(4):1675-1682. doi: 10.1007/s00464-017-5846-9. Epub 2017 Dec 7. PMID: 29218660; PMCID: PMC6690434.
Bydder M, Hamilton G, de Rochefort L, Desai A, Heba ER, Loomba R, Schwimmer JB, Szeverenyi NM, Sirlin CB. Sources of systematic error in proton density fat fraction (PDFF) quantification in the liver evaluated from magnitude images with different numbers of echoes. NMR Biomed. 2018 Jan;31(1):10.1002/nbm.3843. doi: 10.1002/nbm.3843. Epub 2017 Nov 12. PMID: 29130539; PMCID: PMC5761676.
Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B. Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2017 Sep;1(7):609-622. doi: 10.1002/hep4.1068. Epub 2017 Jul 17. PMID: 29130075; PMCID: PMC5679472.
Goyal NP, Schwimmer JB. The Genetics of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2018 Feb;22(1):59-71. doi: 10.1016/j.cld.2017.08.002. Epub 2017 Oct 5. PMID: 29128061; PMCID: PMC5693307.
Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. Response to the Letters Regarding the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition NAFLD Guidelines. J Pediatr Gastroenterol Nutr. 2017 Nov;65(5):e115-e116. doi: 10.1097/MPG.0000000000001731. PMID: 29059122.
Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB. Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2018 Feb;47(2):418-424. doi: 10.1002/jmri.25748. Epub 2017 May 25. PMID: 28543915; PMCID: PMC5702271.
Osier E, Wang AS, Tollefson MM, Cordoro KM, Daniels SR, Eichenfield A, Gelfand JM, Gottlieb AB, Kimball AB, Lebwohl M, Mehta NN, Paller AS, Schwimmer JB, Styne DM, Van Voorhees AS, Tom WL, Eichenfield LF. Pediatric Psoriasis Comorbidity Screening Guidelines. JAMA Dermatol. 2017 Jul 1;153(7):698-704. doi: 10.1001/jamadermatol.2017.0499. PMID: 28514463; PMCID: PMC5748031.
Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. Hepatology. 2017 Nov;66(5):1474-1485. doi: 10.1002/hep.29241. Epub 2017 Oct 9. PMID: 28493388; PMCID: PMC5650504.
Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children. J Pediatr. 2017 Aug;187:141-146.e1. doi: 10.1016/j.jpeds.2017.03.007. Epub 2017 Mar 30. PMID: 28366357; PMCID: PMC5533631.
Haufe WM, Wolfson T, Hooker CA, Hooker JC, Covarrubias Y, Schlein AN, Hamilton G, Middleton MS, Angeles JE, Hernando D, Reeder SB, Schwimmer JB, Sirlin CB. Accuracy of PDFF estimation by magnitude-based and complex-based MRI in children with MR spectroscopy as a reference. J Magn Reson Imaging. 2017 Dec;46(6):1641-1647. doi: 10.1002/jmri.25699. Epub 2017 Mar 21. PMID: 28323377; PMCID: PMC5608618.
Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network. In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. Clin Gastroenterol Hepatol. 2018 Mar;16(3):438-446.e1. doi: 10.1016/j.cgh.2017.02.030. Epub 2017 Mar 7. PMID: 28286193; PMCID: PMC5589478.
Remigio-Baker RA, Allison MA, Forbang NI, Loomba R, Anderson CAM, Budoff M, Schwimmer JB, Blumenthal RS, Ouyang P, Criqui MH. Race/ethnic and sex disparities in the non-alcoholic fatty liver disease-abdominal aortic calcification association: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2017 Mar;258:89-96. doi: 10.1016/j.atherosclerosis.2016.11.021. Epub 2016 Nov 17. PMID: 28235711; PMCID: PMC5502083.
Manning P, Murphy P, Wang K, Hooker J, Wolfson T, Middleton MS, Newton KP, Behling C, Awai HI, Durelle J, Paiz MN, Angeles JE, De La Pena D, McCutchan JA, Schwimmer JB, Sirlin CB. Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease: A MAGNET study. J Magn Reson Imaging. 2017 Oct;46(4):1149-1158. doi: 10.1002/jmri.25663. Epub 2017 Feb 22. PMID: 28225568; PMCID: PMC5568908.
Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). J Pediatr Gastroenterol Nutr. 2017 Feb;64(2):319-334. doi: 10.1097/MPG.0000000000001482. PMID: 28107283; PMCID: PMC5413933.
Yu NY, Wolfson T, Middleton MS, Hamilton G, Gamst A, Angeles JE, Schwimmer JB, Sirlin CB. Bone marrow fat content is correlated with hepatic fat content in paediatric non-alcoholic fatty liver disease. Clin Radiol. 2017 May;72(5):425.e9-425.e14. doi: 10.1016/j.crad.2016.11.017. Epub 2017 Jan 5. PMID: 28063601; PMCID: PMC5376517.
Remigio-Baker RA, Allison MA, Forbang NI, Loomba R, Anderson CAM, Budoff M, Schwimmer JB, Blumenthal RS, Ouyang P, Criqui MH. Race/ethnic and sex disparities in the non-alcoholic fatty liver disease-abdominal aortic calcification association: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2017 Mar;258:89-96. doi: 10.1016/j.atherosclerosis.2016.11.021. Epub 2016 Nov 17. PMID: 28235711; PMCID: PMC5502083.
Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van Natta ML, Clark JM, Tonascia J, Doo E; NASH CRN. In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores. Gastroenterology. 2016 Dec;151(6):1141-1154.e9. doi: 10.1053/j.gastro.2016.08.027. Epub 2016 Aug 26. PMID: 27569726; PMCID: PMC5124386.
Nelson JE, Handa P, Aouizerat B, Wilson L, Vemulakonda LA, Yeh MM, Kowdley KV; NASH Clinical Research Network. Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms. Aliment Pharmacol Ther. 2016 Dec;44(11-12):1253-1264. doi: 10.1111/apt.13824. Epub 2016 Oct 11. PMID: 27730688; PMCID: PMC5118184.
Newton KP, Hou J, Crimmins NA, Lavine JE, Barlow SE, Xanthakos SA, Africa J, Behling C, Donithan M, Clark JM, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network. Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. JAMA Pediatr. 2016 Oct 3;170(10):e161971. doi: 10.1001/jamapediatrics.2016.1971. Epub 2016 Oct 3. PMID: 27478956; PMCID: PMC5479314.
Goyal NP, Schwimmer JB. The Progression and Natural History of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2016 May;20(2):325-38. doi: 10.1016/j.cld.2015.10.003. Epub 2015 Dec 14. PMID: 27063272; PMCID: PMC4829737.
Africa JA, Newton KP, Schwimmer JB. Lifestyle Interventions Including Nutrition, Exercise, and Supplements for Nonalcoholic Fatty Liver Disease in Children. Dig Dis Sci. 2016 May;61(5):1375-86. doi: 10.1007/s10620-016-4126-1. Epub 2016 Apr 4. PMID: 27041377; PMCID: PMC4848041.
Nobili V, Alisi A, Newton KP, Schwimmer JB. Comparison of the Phenotype and Approach to Pediatric vs Adult Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2016 Jun;150(8):1798-810. doi: 10.1053/j.gastro.2016.03.009. Epub 2016 Mar 19. PMID: 27003600; PMCID: PMC4887388.
Kohli R, Sunduram S, Mouzaki M, Ali S, Sathya P, Abrams S, Xanthakos SA, Vos M, Schwimmer JB. Pediatric Nonalcoholic Fatty Liver Disease: A Report from the Expert Committee on Nonalcoholic Fatty Liver Disease (ECON). J Pediatr. 2016 May;172:9-13. doi: 10.1016/j.jpeds.2015.12.016. Epub 2016 Jan 1. PMID: 26749112; PMCID: PMC4846502.
Saab S, Manne V, Nieto J, Schwimmer JB, Chalasani NP. Nonalcoholic Fatty Liver Disease in Latinos. Clin Gastroenterol Hepatol. 2016 Jan;14(1):5-12; quiz e9-10. doi: 10.1016/j.cgh.2015.05.001. Epub 2015 May 11. PMID: 25976180.
Goyal NP, Schwimmer JB. The Progression and Natural History of Pediatric Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2016 May;20(2):325-38. doi: 10.1016/j.cld.2015.10.003. Epub 2015 Dec 14. PMID: 27063272; PMCID: PMC4829737.
Achmad E, Yokoo T, Hamilton G, Heba ER, Hooker JC, Changchien C, Schroeder M, Wolfson T, Gamst A, Schwimmer JB, Lavine JE, Sirlin CB, Middleton MS. Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease. Abdom Imaging. 2015 Oct;40(8):3084-90. doi: 10.1007/s00261-015-0506-9. PMID: 26205992; PMCID: PMC4630122.
Saab S, Manne V, Nieto J, Schwimmer JB, Chalasani NP. Nonalcoholic Fatty Liver Disease in Latinos. Clin Gastroenterol Hepatol. 2016 Jan;14(1):5-12; quiz e9-10. doi: 10.1016/j.cgh.2015.05.001. Epub 2015 May 11. PMID: 25976180.
Xanthakos SA, Schwimmer JB. Paediatric gastroenterology. On a knife-edge--weight-loss surgery for NAFLD in adolescents. Nat Rev Gastroenterol Hepatol. 2015 Jun;12(6):316-8. doi: 10.1038/nrgastro.2015.59. Epub 2015 Apr 14. PMID: 25869913; PMCID: PMC4620919.
Zand KA, Shah A, Heba E, Wolfson T, Hamilton G, Lam J, Chen J, Hooker JC, Gamst AC, Middleton MS, Schwimmer JB, Sirlin CB. Accuracy of multiecho magnitude-based MRI (M-MRI) for estimation of hepatic proton density fat fraction (PDFF) in children. J Magn Reson Imaging. 2015 Nov;42(5):1223-32. doi: 10.1002/jmri.24888. Epub 2015 Apr 3. PMID: 25847512; PMCID: PMC4592685.
Corey KE, Vuppalanchi R, Vos M, Kohli R, Molleston JP, Wilson L, Unalp-Arida A, Cummings OW, Lavine JE, Chalasani N; Nonalcoholic Steatohepatitis Clinical Research Network. Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):360-7. doi: 10.1097/MPG.0000000000000584. PMID: 25714579; PMCID: PMC4341955.
Artz NS, Haufe WM, Hooker CA, Hamilton G, Wolfson T, Campos GM, Gamst AC, Schwimmer JB, Sirlin CB, Reeder SB. Reproducibility of MR-based liver fat quantification across field strength: Same-day comparison between 1.5T and 3T in obese subjects. J Magn Reson Imaging. 2015 Sep;42(3):811-7. doi: 10.1002/jmri.24842. Epub 2015 Jan 23. PMID: 25620624; PMCID: PMC4803480.
Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, Lam J, Hooker JC, Hamilton G, Fontanesi J, Sirlin CB. Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. Hepatology. 2015 Jun;61(6):1887-95. doi: 10.1002/hep.27666. Epub 2015 Feb 5. PMID: 25529941; PMCID: PMC4670559.
Ugalde-Nicalo PA, Schwimmer JB. On the origin of pediatric nonalcoholic Fatty liver disease. J Pediatr Gastroenterol Nutr. 2015 Feb;60(2):147-8. doi: 10.1097/MPG.0000000000000618. PMID: 25373858; PMCID: PMC4308480.
Schwimmer JB, Zepeda A, Newton KP, Xanthakos SA, Behling C, Hallinan EK, Donithan M, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network. Longitudinal assessment of high blood pressure in children with nonalcoholic fatty liver disease. PLoS One. 2014 Nov 24;9(11):e112569. doi: 10.1371/journal.pone.0112569. PMID: 25419656; PMCID: PMC4242611.
Vuppalanchi R, Jain AK, Deppe R, Yates K, Comerford M, Masuoka HC, Neuschwander-Tetri BA, Loomba R, Brunt EM, Kleiner DE, Molleston JP, Schwimmer JB, Lavine JE, Tonascia J, Chalasani N. Relationship between changes in serum levels of keratin 18 and changes in liver histology in children and adults with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2014 Dec;12(12):2121-30.e1-2. doi: 10.1016/j.cgh.2014.05.010. Epub 2014 May 17. PMID: 24846279; PMCID: PMC4830682.
Molleston JP, Schwimmer JB, Yates KP, Murray KF, Cummings OW, Lavine JE, Brunt EM, Scheimann AO, Unalp-Arida A; NASH Clinical Research Network. Histological abnormalities in children with nonalcoholic fatty liver disease and normal or mildly elevated alanine aminotransferase levels. J Pediatr. 2014 Apr;164(4):707-713.e3. doi: 10.1016/j.jpeds.2013.10.071. Epub 2013 Dec 19. PMID: 24360992; PMCID: PMC3962701.
Schwimmer JB, Newton KP, Awai HI, Choi LJ, Garcia MA, Ellis LL, Vanderwall K, Fontanesi J. Paediatric gastroenterology evaluation of overweight and obese children referred from primary care for suspected non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2013 Nov;38(10):1267-77. doi: 10.1111/apt.12518. Epub 2013 Oct 1. PMID: 24117728; PMCID: PMC3984047.
Awai HI, Newton KP, Sirlin CB, Behling C, Schwimmer JB. Evidence and recommendations for imaging liver fat in children, based on systematic review. Clin Gastroenterol Hepatol. 2014 May;12(5):765-73. doi: 10.1016/j.cgh.2013.09.050. Epub 2013 Sep 30. PMID: 24090729; PMCID: PMC3969892.
Hoofnagle JH, Van Natta ML, Kleiner DE, Clark JM, Kowdley KV, Loomba R, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J; Non-alcoholic Steatohepatitis Clinical Research Network (NASH CRN). Vitamin E and changes in serum alanine aminotransferase levels in patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2013 Jul;38(2):134-43. doi: 10.1111/apt.12352. Epub 2013 May 29. PMID: 23718573; PMCID: PMC3775262.
Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb;39(2):440-7. doi: 10.1002/jmri.24153. Epub 2013 Apr 17. PMID: 23596052; PMCID: PMC3732566.
Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB. Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May;267(2):422-31. doi: 10.1148/radiol.12120896. Epub 2013 Feb 4. PMID: 23382291; PMCID: PMC3632805.
Schwimmer JB. Clinical trials for adolescent obesity: cooking up an alphabet stew of what to do. JAMA Pediatr. 2013 Apr;167(4):391-3. doi: 10.1001/jamapediatrics.2013.1661. PMID: 23381196.
Swiderska-Syn M, Suzuki A, Guy CD, Schwimmer JB, Abdelmalek MF, Lavine JE, Diehl AM. Hedgehog pathway and pediatric nonalcoholic fatty liver disease. Hepatology. 2013 May;57(5):1814-25. doi: 10.1002/hep.26230. Epub 2013 Apr 1. PMID: 23300059; PMCID: PMC3637920.
Nelson JE, Brunt EM, Kowdley KV; Nonalcoholic Steatohepatitis Clinical Research Network. Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. Hepatology. 2012 Nov;56(5):1730-40. doi: 10.1002/hep.25856. Epub 2012 Sep 20. PMID: 22611049; PMCID: PMC3462887.
Dunn W, Sanyal AJ, Brunt EM, Unalp-Arida A, Donohue M, McCullough AJ, Schwimmer JB. Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD). J Hepatol. 2012 Aug;57(2):384-91. doi: 10.1016/j.jhep.2012.03.024. Epub 2012 Apr 17. PMID: 22521357; PMCID: PMC3399018.
Suzuki A, Abdelmalek MF, Schwimmer JB, Lavine JE, Scheimann AO, Unalp-Arida A, Yates KP, Sanyal AJ, Guy CD, Diehl AM; Nonalcoholic Steatohepatitis Clinical Research Network. Association between puberty and features of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2012 Jul;10(7):786-94. doi: 10.1016/j.cgh.2012.01.020. Epub 2012 Feb 14. PMID: 22343513; PMCID: PMC3382041.
Guerrerio AL, Colvin RM, Schwartz AK, Molleston JP, Murray KF, Diehl A, Mohan P, Schwimmer JB, Lavine JE, Torbenson MS, Scheimann AO. Choline intake in a large cohort of patients with nonalcoholic fatty liver disease. Am J Clin Nutr. 2012 Apr;95(4):892-900. doi: 10.3945/ajcn.111.020156. Epub 2012 Feb 15. PMID: 22338037; PMCID: PMC3302364.
Guy CD, Suzuki A, Zdanowicz M, Abdelmalek MF, Burchette J, Unalp A, Diehl AM; NASH CRN. Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease. Hepatology. 2012 Jun;55(6):1711-21. doi: 10.1002/hep.25559. Epub 2012 Apr 18. PMID: 22213086; PMCID: PMC3499103.
Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE; NASH CRN Research Group. Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):90-6. doi: 10.1097/MPG.0b013e318229da1a. PMID: 22197855; PMCID: PMC3208079.
Pardee PE, Dunn W, Schwimmer JB. Non-alcoholic fatty liver disease is associated with low bone mineral density in obese children. Aliment Pharmacol Ther. 2012 Jan;35(2):248-54. doi: 10.1111/j.1365-2036.2011.04924.x. Epub 2011 Nov 24. PMID: 22111971; PMCID: PMC4624396.
Pardee PE, Dunn W, Schwimmer JB. Non-alcoholic fatty liver disease is associated with low bone mineral density in obese children. Aliment Pharmacol Ther. 2012 Jan;35(2):248-54. doi: 10.1111/j.1365-2036.2011.04924.x. Epub 2011 Nov 24. PMID: 22111971; PMCID: PMC4624396.
Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR; Nonalcoholic Steatohepatitis Clinical Research Network. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA. 2011 Apr 27;305(16):1659-68. doi: 10.1001/jama.2011.520. PMID: 21521847; PMCID: PMC3110082.
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators; Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011 Mar;7(3):e1001324. doi: 10.1371/journal.pgen.1001324. Epub 2011 Mar 10. PMID: 21423719; PMCID: PMC3053321.
Dohil R, Schmeltzer S, Cabrera BL, Wang T, Durelle J, Duke KB, Schwimmer JB, Lavine JE. Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2011 May;33(9):1036-44. doi: 10.1111/j.1365-2036.2011.04626.x. Epub 2011 Mar 13. PMID: 21395631.
Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA; NASH Clinical Research Network (CRN). Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. Hepatology. 2011 Mar;53(3):810-20. doi: 10.1002/hep.24127. Epub 2011 Feb 11. PMID: 21319198; PMCID: PMC3079483.
Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin CB. Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology. 2011 Mar;258(3):749-59. doi: 10.1148/radiol.10100659. Epub 2011 Jan 6. PMID: 21212366; PMCID: PMC3042639.
Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, Schwimmer JB; NASH CRN Research Group. Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. Am J Gastroenterol. 2011 Mar;106(3):460-8; quiz 469. doi: 10.1038/ajg.2010.488. Epub 2011 Jan 4. PMID: 21206486; PMCID: PMC3070294.
Lindbäck SM, Gabbert C, Johnson BL, Smorodinsky E, Sirlin CB, Garcia N, Pardee PE, Kistler KD, Schwimmer JB. Pediatric nonalcoholic fatty liver disease: a comprehensive review. Adv Pediatr. 2010;57(1):85-140. doi: 10.1016/j.yapd.2010.08.006. PMID: 21056736.
Gabbert C, Donohue M, Arnold J, Schwimmer JB. Adenovirus 36 and obesity in children and adolescents. Pediatrics. 2010 Oct;126(4):721-6. doi: 10.1542/peds.2009-3362. Epub 2010 Sep 20. PMID: 20855385.
Neuschwander-Tetri BA, Clark JM, Bass NM, Van Natta ML, Unalp-Arida A, Tonascia J, Zein CO, Brunt EM, Kleiner DE, McCullough AJ, Sanyal AJ, Diehl AM, Lavine JE, Chalasani N, Kowdley KV; NASH Clinical Research Network. Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease. Hepatology. 2010 Sep;52(3):913-24. doi: 10.1002/hep.23784. PMID: 20648476; PMCID: PMC3070295.
Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR; NASH CRN. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med. 2010 May 6;362(18):1675-85. doi: 10.1056/NEJMoa0907929. Epub 2010 Apr 28. PMID: 20427778; PMCID: PMC2928471.
Patton HM, Yates K, Unalp-Arida A, Behling CA, Huang TT, Rosenthal P, Sanyal AJ, Schwimmer JB, Lavine JE. Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease. Am J Gastroenterol. 2010 Sep;105(9):2093-102. doi: 10.1038/ajg.2010.152. Epub 2010 Apr 6. PMID: 20372110; PMCID: PMC3070291.
Abdelmalek MF, Suzuki A, Guy C, Unalp-Arida A, Colvin R, Johnson RJ, Diehl AM; Nonalcoholic Steatohepatitis Clinical Research Network. Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology. 2010 Jun;51(6):1961-71. doi: 10.1002/hep.23535. PMID: 20301112; PMCID: PMC2922495.
Schwimmer JB, Dunn W, Norman GJ, Pardee PE, Middleton MS, Kerkar N, Sirlin CB. SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. Gastroenterology. 2010 Apr;138(4):1357-64, 1364.e1-2. doi: 10.1053/j.gastro.2009.12.052. Epub 2010 Jan 11. PMID: 20064512; PMCID: PMC2846968.
Kistler KD, Molleston J, Unalp A, Abrams SH, Behling C, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Symptoms and quality of life in obese children and adolescents with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2010 Feb 1;31(3):396-406. doi: 10.1111/j.1365-2036.2009.04181.x. Epub 2009 Oct 23. PMID: 19863497; PMCID: PMC2807909.
Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network Research Group. Treatment of nonalcoholic fatty liver disease in children: TONIC trial design. Contemp Clin Trials. 2010 Jan;31(1):62-70. doi: 10.1016/j.cct.2009.09.001. Epub 2009 Sep 15. PMID: 19761871; PMCID: PMC2936451.
Barshop NJ, Francis CS, Schwimmer JB, Lavine JE. Nonalcoholic fatty liver disease as a comorbidity of childhood obesity. Ped Health. 2009 Jun 1;3(3):271-281. doi: 10.2217/phe.09.21. PMID: 20556232; PMCID: PMC2885801.
Kistler KD, Molleston J, Unalp A, Abrams SH, Behling C, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Symptoms and quality of life in obese children and adolescents with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2010 Feb 1;31(3):396-406. doi: 10.1111/j.1365-2036.2009.04181.x. Epub 2009 Oct 23. PMID: 19863497; PMCID: PMC2807909.
Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network Research Group. Treatment of nonalcoholic fatty liver disease in children: TONIC trial design. Contemp Clin Trials. 2010 Jan;31(1):62-70. doi: 10.1016/j.cct.2009.09.001. Epub 2009 Sep 15. PMID: 19761871; PMCID: PMC2936451.
Pardee PE, Lavine JE, Schwimmer JB. Diagnosis and treatment of pediatric nonalcoholic steatohepatitis and the implications for bariatric surgery. Semin Pediatr Surg. 2009 Aug;18(3):144-51. doi: 10.1053/j.sempedsurg.2009.04.004. PMID: 19573756; PMCID: PMC2761012.
Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin CB. Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging. 2009 Jul;30(1):145-52. doi: 10.1002/jmri.21809. PMID: 19557733; PMCID: PMC2982807.
Shah AG, Lydecker A, Murray K, Tetri BN, Contos MJ, Sanyal AJ; Nash Clinical Research Network. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2009 Oct;7(10):1104-12. doi: 10.1016/j.cgh.2009.05.033. Epub 2009 Jun 10. PMID: 19523535; PMCID: PMC3079239.
David K, Kowdley KV, Unalp A, Kanwal F, Brunt EM, Schwimmer JB; NASH CRN Research Group. Quality of life in adults with nonalcoholic fatty liver disease: baseline data from the nonalcoholic steatohepatitis clinical research network. Hepatology. 2009 Jun;49(6):1904-12. doi: 10.1002/hep.22868. PMID: 19434741; PMCID: PMC2692572.
Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB. Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. Radiology. 2009 Apr;251(1):67-76. doi: 10.1148/radiol.2511080666. Epub 2009 Feb 12. PMID: 19221054; PMCID: PMC2663579.
Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB. Heritability of nonalcoholic fatty liver disease. Gastroenterology. 2009 May;136(5):1585-92. doi: 10.1053/j.gastro.2009.01.050. Epub 2009 Jan 25. PMID: 19208353; PMCID: PMC3397140.
Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin CB. Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. Radiographics. 2009 Jan-Feb;29(1):231-60. doi: 10.1148/rg.291075123. PMID: 19168847.
Caprio S, Daniels SR, Drewnowski A, Kaufman FR, Palinkas LA, Rosenbloom AL, Schwimmer JB. Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment. Obesity (Silver Spring). 2008 Dec;16(12):2566-77. doi: 10.1038/oby.2008.398. PMID: 19279654.
Patton HM, Lavine JE, Van Natta ML, Schwimmer JB, Kleiner D, Molleston J; Nonalcoholic Steatohepatitis Clinical Research Network. Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis. Gastroenterology. 2008 Dec;135(6):1961-1971.e2. doi: 10.1053/j.gastro.2008.08.050. Epub 2008 Sep 3. PMID: 19013463; PMCID: PMC2628583.
Rubinstein E, Lavine JE, Schwimmer JB. Hepatic, cardiovascular, and endocrine outcomes of the histological subphenotypes of nonalcoholic fatty liver disease. Semin Liver Dis. 2008 Nov;28(4):380-5. doi: 10.1055/s-0028-1091982. Epub 2008 Oct 27. PMID: 18956294.
Caprio S, Daniels SR, Drewnowski A, Kaufman FR, Palinkas LA, Rosenbloom AL, Schwimmer JB. Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment: a consensus statement of Shaping America's Health and the Obesity Society. Diabetes Care. 2008 Nov;31(11):2211-21. doi: 10.2337/dc08-9024. PMID: 18955718; PMCID: PMC2571048.
Dunn W, Xu R, Wingard DL, Rogers C, Angulo P, Younossi ZM, Schwimmer JB. Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study. Am J Gastroenterol. 2008 Sep;103(9):2263-71. doi: 10.1111/j.1572-0241.2008.02034.x. Epub 2008 Aug 5. PMID: 18684196; PMCID: PMC2574666.
Andrews DB, Schwimmer JB, Lavine JE. Fast break on the fat brake: mechanism of peroxisome proliferator-activated receptor-delta regulation of lipid accumulation in hepatocytes. Hepatology. 2008 Aug;48(2):355-7. doi: 10.1002/hep.22505. PMID: 18666254.
Schwimmer JB, Pardee PE, Lavine JE, Blumkin AK, Cook S. Cardiovascular risk factors and the metabolic syndrome in pediatric nonalcoholic fatty liver disease. Circulation. 2008 Jul 15;118(3):277-83. doi: 10.1161/CIRCULATIONAHA.107.739920. Epub 2008 Jun 30. PMID: 18591439; PMCID: PMC2996820.
Dunn W, Xu R, Schwimmer JB. Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. Hepatology. 2008 Jun;47(6):1947-54. doi: 10.1002/hep.22292. PMID: 18454505; PMCID: PMC6658188.
Dunn W, Schwimmer JB. The obesity epidemic and nonalcoholic fatty liver disease in children. Curr Gastroenterol Rep. 2008 Feb;10(1):67-72. doi: 10.1007/s11894-008-0011-1. PMID: 18417045.
Pardee PE, Norman GJ, Lustig RH, Preud'homme D, Schwimmer JB. Television viewing and hypertension in obese children. Am J Prev Med. 2007 Dec;33(6):439-43. doi: 10.1016/j.amepre.2007.07.036. PMID: 18022058.
Schwimmer JB. Definitive diagnosis and assessment of risk for nonalcoholic fatty liver disease in children and adolescents. Semin Liver Dis. 2007 Aug;27(3):312-8. doi: 10.1055/s-2007-985075. PMID: 17682977.
Varni JW, Lane MM, Burwinkle TM, Fontaine EN, Youssef NN, Schwimmer JB, Pardee PE, Pohl JF, Easley DJ. Health-related quality of life in pediatric patients with irritable bowel syndrome: a comparative analysis. J Dev Behav Pediatr. 2006 Dec;27(6):451-8. doi: 10.1097/00004703-200612000-00001. PMID: 17164617.
Patton HM, Sirlin C, Behling C, Middleton M, Schwimmer JB, Lavine JE. Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. J Pediatr Gastroenterol Nutr. 2006 Oct;43(4):413-27. doi: 10.1097/01.mpg.0000239995.58388.56. PMID: 17033514.
Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C. Prevalence of fatty liver in children and adolescents. Pediatrics. 2006 Oct;118(4):1388-93. doi: 10.1542/peds.2006-1212. PMID: 17015527.
Lavine JE, Schwimmer JB. Clinical Research Network launches TONIC trial for treatment of nonalcoholic fatty liver disease in children. J Pediatr Gastroenterol Nutr. 2006 Feb;42(2):129-30. doi: 10.1097/01.mpg.0000189332.77644.1f. PMID: 16456401.
Xanthakos SA, Schwimmer JB, Melin-Aldana H, Rothenberg ME, Witte DP, Cohen MB. Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. J Pediatr Gastroenterol Nutr. 2005 Jul;41(1):16-22. doi: 10.1097/01.mpg.0000161039.96200.f1. PMID: 15990624.
Schwimmer JB, McGreal N, Deutsch R, Finegold MJ, Lavine JE. Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents. Pediatrics. 2005 May;115(5):e561-5. doi: 10.1542/peds.2004-1832. PMID: 15867021.
Schwimmer JB, Middleton MS, Deutsch R, Lavine JE. A phase 2 clinical trial of metformin as a treatment for non-diabetic paediatric non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2005 Apr 1;21(7):871-9. doi: 10.1111/j.1365-2036.2005.02420.x. PMID: 15801922.
Schwimmer JB, Khorram O, Chiu V, Schwimmer WB. Abnormal aminotransferase activity in women with polycystic ovary syndrome. Fertil Steril. 2005 Feb;83(2):494-7. doi: 10.1016/j.fertnstert.2004.08.020. PMID: 15705403.
Lavine JE, Schwimmer JB. Nonalcoholic fatty liver disease in the pediatric population. Clin Liver Dis. 2004 Aug;8(3):549-58, viii-ix. doi: 10.1016/j.cld.2004.04.010. PMID: 15331063.
Schwimmer JB. Managing overweight in older children and adolescents. Pediatr Ann. 2004 Jan;33(1):39-44. doi: 10.3928/0090-4481-20040101-11. PMID: 14981868.
Schwimmer JB, Lavine JE. Lumen and the liver--together again in NASHville. J Pediatr Gastroenterol Nutr. 2003 Oct;37(4):523-4. doi: 10.1097/00005176-200310000-00024. PMID: 14579849.
Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis-Clinical Research Network. Pediatric initiatives within the Nonalcoholic Steatohepatitis-Clinical Research Network (NASH CNR). J Pediatr Gastroenterol Nutr. 2003 Sep;37(3):220-1. doi: 10.1097/00005176-200309000-00002. PMID: 12971361.
Schwimmer JB, Burwinkle TM, Varni JW. Health-related quality of life of severely obese children and adolescents. JAMA. 2003 Apr 9;289(14):1813-9. doi: 10.1001/jama.289.14.1813. PMID: 12684360.
Schwimmer JB, Ee L, Zheng S, Tso P. Glutamine promotes triglyceride absorption in a dose-dependent manner. Am J Physiol Gastrointest Liver Physiol. 2002 Feb;282(2):G317-23. doi: 10.1152/ajpgi.2002.282.2.G317. PMID: 11804853.
Schwimmer JB, Balistreri WF. Transmission, natural history, and treatment of hepatitis C virus infection in the pediatric population. Semin Liver Dis. 2000;20(1):37-46. doi: 10.1055/s-2000-9257. PMID: 10895430.
