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Department of Pediatrics Department of Pediatrics

Collaborators at UCSD

Richard Gallo, MD, PhD

Richard Gallo, MD, PhD
Professor & Founding Chair
Dept. of Dermatology
Skin Innate Immunity, Cathelicidin AMPs

Ajit Varki, MD

Ajit Varki, MD
Distinguished Professor of Medicine and Cellular & Molecular Medicine
Sialic Acids and Siglecs in Bacterial Host-Pathogen Interactions

Michael Karin, PhD

Michael Karin, PhD
Distinguished Professor of Pharmacology
Innate Immunity, NFkB/IKK and Inflammasome Signaling

Partho Ghosh, PhD

Partho Ghosh, PhD
Professor of Chemistry and Biochemistry
M Protein Structure-Function and GAS Pathogenesis

Pieter Dorrestein, PhD

Pieter Dorrestein, PhD
Associate Professor of Chemistry & Biochemistry and Pharmacy
Imaging Mass Spectrometry in Bacterial Interactions

Jack Dixon, PhD

Jack Dixon, PhD
Professor of Pharmacology and Cellular & Molecular Medicine
Structural and Functional Biochemistry of Bacterial Toxins

Ethan Bier, PhD

Ethan Bier, PhD
Professor of Biological Sciences
Anthrax and Cholera Toxins Endosome Recycling and Cell Junctions

Christopher Glass, MD, PhD

Christopher Glass, MD, PhD
Professor of Medicine and Cellular & Molecular Medicine
Cholesterol Metabolism and Phagocyte Innate Immune Function

William Fenical, PhD

William Fenical, PhD
Distinguished Professor Scripps Institution of Oceanography
Antibiotic Discovery from Deep Ocean Actinomycetes

Laura Crotty Alexander, MD

Laura Crotty Alexander, MD
Assistant Professor of Medicine
HIF regulation of asthma
Cigarette smoke and pulmonary innate immune defense

Edmund Capparelli, PharmD

Edmund Capparelli, PharmD
Professor of Pediatrics and Pharmacy
Developmental Pharmacology and PK/PD of Pediatric Antimicrobial Therapy

Jeffrey Esko, PhD

Jeffrey Esko, PhD
Professor of Cellular & Molecular Medicine
Role of Proteoglycans in Bacterial Host-Pathogen Interactions

Bernhard Palsson, PhD

Bernhard Palsson, PhD
Galletti Professor of Bioengineering
The Systems Biology of Bacterial Evolution of Antibiotic Resistance and Virulence

Emily Troemel, PhD

Emily Troemel, PhD
Associate Professor of Biological Sciences
Innate Immune Responses to Bacterial  Toxins

Michael Burkart, PhD

Michael Burkart, PhD
Professor of Chemistry & Biochemistry
Novel Drug Targets for Antibiotic Resistant Pathogens

Liangfang Zhang, PhD

Liangfang Zhang, PhD
Associate Professor of Nanoengineering
Biomimetic Nanoparticles to Treat and Prevent  Bacterial Infections

Hal Hoffman, MD

Hal Hoffman, MD
Professor of Pediatrics
Inflammasome function in innate immune defense vs. pathogens

David Gonzalez, PhD

David Gonzalez, PhD
Asst. Professor of Pharmacology and Pharmacy
Mass spectrometry approaches to host-pathogen interactions

George Liu, MD, PhD

George Liu, MD, PhD
Professor and Chief Infectious Diseases
Staphyloxanthin and other MRSA immune evasion factors

Collaborators Near and Far

Mark Walker, PhD

Mark Walker, PhD
University of Queensland
Brisbane, Australia

Molecular Pathogenesis and Evolution of Streptococcal Virulence

Randall Johnson, PhD

Randall Johnson, PhD
University of Cambridge
Cambridge, UK
HIF-1 Regulation of Innate Immunity and Inflammation

Eric Oldfield, PhD

Eric Oldfield, PhD
University of Illinois
Urbana-Champaign, Illinois
Medicinal chemistry of virulence factor inhibition in S. aureus

Toby Lawrence, PhD

Toby Lawrence, PhD
Center for Immunology
Marseille-Luminy, France

Effects of bacterial toxins on macrophage immune and inflammatory responses

Emanuel Hanski, PhD

Emanuel Hanski, PhD
Hebrew University
Jerusalem, Israel

Genetic Regulation of Group A Streptococcal Virulence

Bernard Beall, PhD

Bernard Beall, PhD
CDC Streptococcus Laboratory
Atlanta, Georgia
Molecular epidemiology and genetics of GAS

Malak Kotb, PhD

Malak Kotb, PhD
University of North Dakota
Group A Streptococcal Virulence and Immunity

Ze'ev Ronai, PhD

Ze'ev Ronai, PhD
Sanford-Burnham Institute
La Jolla, CA
Autophagy and macrophage innate immune function

Kelly Doran, PhD

Kelly Doran, PhD
Department of Biology
San Diego State University
Bacterial interactions with the blood-brain barrier

Suzan Rooijakkers, PhD

Suzan Rooijakkers, PhD
University Medical Center
Utrecht, Netherlands
Bacterial interactions with serum and the complement system

Annelies Zinkernagel, MD, PhD

Annelies Zinkernagel, MD, PhD
University of Zurich Hospital
Z
urich, Switzerland
Molecular pathogenesis of GAS infection

Maren von Köckritz-Blickwede, PhD

Maren von Köckritz-Blickwede, PhD
University of Hannover
Hannover, Germany

Roles of neutrophil extracellular traps in antibacterial immunity

Shauna McGillivray, PhD

Shauna McGillivray, PhD
Texas Christian University
Fort Worth, Texas
Innate Immune Resistance Factors of Bacillus anthracis

Ramy Aziz, PhD

Ramy Aziz, PhD
Cairo University
Cairo, Egypt & UCSD
Comparative genomics of GAS virulence factors

Jamey Marth, PhD

Jamey Marth, PhD
University of California, Santa Barbara & Sanford-Burnham
Glycoprotein Remodeling in Sepsis, Ashwell-Morell Receptor Function

Nina van Sorge, PharmD, PhD

Nina van Sorge, PharmD, PhD
University Medical Center
Utrecht, Netherlands
Streptococcal group carbohydrate antigens

Mona Johannessen, PhD

Mona Johannessen, PhD
Arctic University of Norway
Tromsø, Norway
Staphylococcal immune evasion virulence factors

Industry Partners

Altermune Technologies

Altermune Technologies
Irvine, CA and London, England
Chemically programmed immunity
vs. antibiotic-resistant pathogens

Aerpio Therapeutics

Aerpio Therapeutics
Cincinnati, Ohio
HIF-1 boosting agents for wound
healing and antibacterial defense

Cellics Therapeutics

Cellics Therapeutics
San Diego, CA
Biomimetic nanoparticles as a sepsis therapeutic

Cidara Therapeutics

Cidara Therapeutics
San Diego, CA
CloudbreakTM technology vs.
fungal and bacterial pathogens

Roche Pharma Research & Early Development (pRED)

Roche Pharma Research & Early Development (pRED)
Basel, Switzlerland
Antibiotic drug discovery

InhibRx

InhibRx
San Diego, CA
Novel immunotherapies for
antibiotic-resistant pathogens